This website uses its own and third-party cookies. Some of these cookies are used to develop analytical statistics of visits to the webpage, others to manage advertising or even others are necessary for the correct management of the site. If you continue to browse or click in accept we consider you accept the conditions for their use. You can get more information, or learn how to change the settings in our cookies policy?
Versión Española Versión Mexicana Ibercampus English Version Version française Versione italiana

25/4/2018  
    Ibercampus  | Editorial Board | Who we are | Ideology | Contact | Advertising rates | Subscription | RSS RSS
Policies
Inclusion policies
R&D
Employment
Economics
Culture
Green strategies
Health
Society and consumer
Sports
Debates
Interviews
Education
Grants & internships
Training
Trends
Enterprises & CSR
 Enterprises & CSR
ACNUR
AEGON
AIR LIQUIDE
ALCATEL-LUCENT
ALLIANZ
ARCELORMITTAL
ASIFIN
ASSICURAZIONI GENERALI
AXA
BANCO SANTANDER
BASF
BAYER
BBVA
BNP PARIBAS
CARREFOUR
DAIMLER AG
DEUTSCHE BANK
DEUTSCHE BÖRSE
DEUTSCHE TELEKOM
E.ON
ENEL
ENI
FORTIS
FRANCE TÉLÉCOM
GROUPE DANONE
IBERDROLA
INDITEX
ING GROUP
INTESA SANPAOLO
L'ORÉAL
LVMH
MUNICH RE
NOKIA
PHILIPS
RENAULT
REPSOL YPF
RWE
SAINT GOBAIN
SANOFI-AVENTIS
SAP AG
SCHNEIDER ELECTRIC
SIEMENS AG
SOCIÉTÉ GÉNÉRALE
SUEZ
TELECOM ITALIA
TELEFÓNICA
TOTAL S.A.
UNICREDIT
UNILEVER
VINCI
VIVENDI
VOLKSWAGEN

SOCIETY AND CONSUMER
Cambridge University

Further evidence shows education reduces risk of Alzheimer´s


New research from Cambridge University, supported by European Union funding, has added weight to the theory that education protects against Alzheimer´s disease.
Ibercampus 8/1/2018 Send to a friend
Comparte esta noticia en TwitterFacebookTwitterdel.icio.usYahooRSS
A study just published in the ‘British Medical Journal’ confirms there is a link between education and the build-up of 'plaques' and 'tangles' of misshapen proteins, which lead to the gradual death of brain cells, characteristic of Alzheimer’s disease.

The causes of the disease are still largely unknown and drugs treatments have suffered disappointing set backs in their development. So the focus of attention is shifting to trying to work out how to reduce the number of cases by tackling risk factors before the disease develops. This could be showing some success: research from the Cambridge Institute of Public Health has shown that the incidence of Alzheimer's is falling in the UK, probably due to improvements in education, and smoking reduction and better diet and exercise.

This latest study, titled ‘To determine which potentially modifiable risk factors, including socioeconomic, lifestyle/dietary, cardiometabolic, and inflammatory factors, are associated with Alzheimer’s disease’ involved 17 008 patients with Alzheimer’s disease and 37 154 controls. It considered 24 potentially modifiable risk factors.

Conventional observational studies have consistently shown that low educational attainment is associated with an increased risk and it has been estimated that 19 % of cases are potentially attributable to low education.

Inconclusive evidence from conventional observational studies indicates that the following are risk factors: obesity; hypertension and high cholesterol in midlife; diabetes; smoking; low vitamin D and folate concentrations; hyperhomocysteinaemia (an abnormally high level of homocysteine in the blood), and high C reactive protein concentrations (an acute-phase protein that serves as an early marker of inflammation or infection). Physical activity, a healthy diet, moderate alcohol drinking, and coffee consumption are associated with decreased risk.

The researchers, in part supported by EU through the COSTREAM project, explain that available evidence is in large part inadequate as observational studies generally rely on self-reported information. They are susceptible to doubts arising from the relationship between cause and effect. Data from randomised trials are scarce and inconclusive.

Bringing new evidence into the debate

Researchers grouped the risks into categories: socioeconomic, lifestyle/dietary, cardiometabolic, and inflammatory. They studied genetic variants that increase the risk of a variety of different environmental risk factors to see if these were more common in 17 000 patients with Alzheimer's disease. Results showed the strongest association with genetic variants that predict higher educational attainment.

‘This provides further strong evidence that education is associated with a reduced risk of Alzheimer's disease,’ says first author Dr Susanna Larsson, ‘It suggests that improving education could have a significant effect on reducing the number of people who suffer from this devastating disease.’

How education might reduce the risk of Alzheimer's is uncertain but it could be related to what is known as 'cognitive reserve', the ability to recruit alternative brain networks, or to use brain structures or networks not normally used, in order to compensate for brain ageing. Other research has shown that the same amount of damage in the brain is associated with less severe and less frequent Alzheimer's in people who have received more education, which could support that theory. The evidence points to the fact that education, which helps to improve brain wiring, could be increasing the reserve of networks the brain can continue to draw on.

COSTREAM (Common mechanisms and pathways in Stroke and Alzheimer's disease) brings together epidemiologists, geneticists, radiologists, neurologists researching the similarities between both conditions, which have an overlapping pathogenesis. The team is harnessing their vast international network in order to link various big datasets along with combining novel analytical strategies with emerging technologies in the field of genomics, metabolomics, and brain MR-imaging.

For more information, please see:
Project website
Source: Based on project information and media reports

Other issues Society and consumer
Europe granted citizenship to almost 1 million persons in 2016
EU financing of free wireless internet hotspots in public spaces
Chișinău, Klaipėda, Greater Nicosia, Yaroslavl and Varaždin European Youth Capital finalist cities
Stephen Hawking dies at the age of 76
Men occupy 75% of the positions of maximum responsibility in the Spanish media
Only 17% of profiles on Wikipedia are of women, let´s bridge the gender gap in the digital space
Holding hands can sync brainwaves, ease pain, study shows
Male teens handle car better than older men, study finds
UN human rights experts urge US Government to protect the rights of ´Dreamers´
The majority of countries are making little or no progress in ending corruption

Subscribe free to our newsletter
Vanity Fea
The Prehistoric Origin of Cinema
José Ángel García Landa
Financial inclusion
Financial Education For All!
Carlos Trias
Brusselian Lights
European elections (I): which words are more used in the European political manifestos?
Raúl Muriel Carrasco
Humor and Political Communication
Comisión de Arbitraje, Quejas y Deontología (Spain) (3) You can´t be too careful
Felicísimo Valbuena
Want your own blog? Want to be read by universities?
Find out here
Books
Will Big Business Destroy Our Planet?
Casey, Michael J.; Vigna, Paul: Cryptocurrency "The Future of Money?"
Eurydice brief: Citizenship Education at School in Europe – 2017
The Future of Work
Ten Great Ideas about Chance
Young Consumer Behaviour "A Research Companion"
Theses and dissertations
1 How travelling in Europe can boost active citizenship
2 EU supports South Africa to boost job creation, small business development and improved governance
3 13 Sites in Africa, Asia, Europe and North America Receive UNESCO Global Geopark Label
4 Employment rate of people aged 20 to 64 in the EU reached a new peak at 72.2% in 2017
5 EU Skills Profile Tool for Third Country Nationals gets an upgrade
6 How fair do Europeans think life in the EU is?
7 Share of early leavers from education and training continues decreasing in the EU
8 Mariana Costa"We want to train young women to make them talented and competitive software developer"
9 Apply for the International Youth Forum on Creativity and Heritage along the Silk Roads in May 2018
10 Will Big Business Destroy Our Planet?
Legal Advise | Privacy Policy | Editorial Board | Who we are | Ideology | Contact | Advertising rates | RSS RSS